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Article

Natural killer cell TGF-β signaling regulates senolytic activity and vascular patterning in the postnatal lung

2025-09-04

Abstract excerpt

<h4>Background</h4> Bronchopulmonary dysplasia (BPD) is a disease of neonatal lung development that is linked to impaired pulmonary vascularization, dysregulated transforming growth factor-β (TGF-β) signaling and the accumulation of senescent cells. Despite the established role for TGF-β signaling in promoting vascular remodeling and suppressing the senolytic activity of natural killer (NK) cells, the contributio...

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Literature Corpus work
b2bd927e-f4d1-58c4-b0c0-8bc5de01ca0b
DOI
10.1101/2025.08.29.673190
Open publication

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Natural killer cell TGF-β signaling regulates senolytic activity and vascular patterning in the postnatal lungDOI 10.1101/2025.08.29.673190
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