Article

A Multiscale Computational Architecture to Study Signaling Dynamics at Cell-Cell Interfaces

2026-03-18

Abstract excerpt

<h4>ABSTRACT</h4> Intercellular communication is governed by the spatiotemporal dynamics of protein complexes at the cell-cell interface. However, conventional static interaction models fail to incorporate key physical constraints, such as steric hindrance, spatial compartmentalization, and dimensionality reduction that regulate complex assembly in vivo. To bridge the gap between static network topology and dynam...

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Literature Corpus work: b2a1226f-2618-52c5-ab6a-da0491bfa383
DOI: 10.64898/2026.03.16.712104

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