Article

Alterations of genomic imprinting appear during the reprogramming of adult neural stem cells

2024-01-24

Abstract excerpt

Genomic imprinting is an epigenetic mechanism that causes monoallelic expression of genes depending on their parental origin. Loss of imprinting (LOI) is associated with cancer progression and human imprinting disorders (IDs), impacting foetal development, metabolism and cognition. Imprinted genes, organized in clusters, rely on methylation at imprint control regions (ICRs), which are differentially methylated reg...

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Literature Corpus work: b25c745e-620a-5910-b7cd-63a28f63ffe8
DOI: 10.1101/2024.01.23.576820

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