Article
Genomic imprinting in mammals.
Cold Spring Harbor perspectives in biology - 1 Feb 2014
Barlow Denise P, Bartolomei Marisa S
Abstract excerpt
Genomic imprinting affects a subset of genes in mammals and results in a monoallelic, parental-specific expression pattern. Most of these genes are located in clusters that are regulated through the use of insulators or long noncoding RNAs (lncRNAs). To distinguish the parental alleles, imprinted genes are epigenetically marked in gametes at imprinting control elements through the use of DNA methylation at the...
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