Article
Modeling Genomic Imprinting Disorders Using Induced Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Chamberlain Stormy J, Germain Noelle D, Chen Pin-Fang, Hsiao Jack S, Glatt-Deeley Heather
Abstract excerpt
Induced pluripotent stem cell (iPSC) technology has allowed for the invaluable modeling of many genetic disorders including disorders associated with genomic imprinting. Genomic imprinting involves differential DNA and histone methylation and results in allele-specific gene expression. Most of th...
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