Article

Evaluation of a Next Generation Sequencing Assay for Hepatitis B Antiviral Drug Resistance on the Oxford Nanopore System

2024-10-02

Abstract excerpt

<h4>Background</h4> Next-generation sequencing (NGS) for Hepatitis B virus (HBV) antiviral resistance (AVR) testing is a highly sensitive diagnostic method, able to detect low-level mutant subpopulations. Our clinical virology laboratory previously transitioned from DNA hybridization (INNO-LiPA) to NGS, initially with the GS Junior System and subsequently the MiSeq. The Oxford Nanopore Technology (ONT) sequencing...

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Literature Corpus work: b2599639-cea5-551e-8bf6-af32b32eaec8
DOI: 10.1101/2024.10.01.24314730

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