Article
Leveraging the Oxford Nanopore MinION sequencing platform for HIV-1 drug resistance surveillance in resource-limited settings: a post-COVID implementation opportunity.
Virology journal - 15 Mar 2026
Washaya Tendai, Chimukangara Benjamin, Mayini Justin, Bote Sandra, Chin'ombe Nyasha, Munyati Shungu, Manasa Justen
Abstract excerpt
BACKGROUND: HIV drug resistance (HIVDR) testing remains essential for optimizing antiretroviral therapy (ART), yet access remains constrained by high cost, low throughput, and limited availability of Sanger sequencing in resource-limited settings (RLS). Recent improvements in Oxford Nanopore Technologies (ONT) sequencing offer a potential alternative, especially following the expansion of genomic surveillance...
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