Article

The Host Interactome of Spike Expands the Tropism of SARS-CoV-2

2021-02-16

Abstract excerpt

The SARS-CoV-2 virus causes severe acute respiratory syndrome (COVID-19) and has rapidly created a global pandemic. Patients that survive may face a slow recovery with long lasting side effects that can afflict different organs. SARS-CoV-2 primarily infects epithelial airway cells that express the host entry receptor Angiotensin Converting Enzyme 2 (ACE2) which binds to spike protein trimers on the surface of SARS...

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Literature Corpus work: b24e4443-2129-59e7-949a-e57bd2880f96
DOI: 10.1101/2021.02.16.431318

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