Article

VLP-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice

2023-09-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Neoantigens are patient- and tumor-specific peptides that arise from somatic mutations. They stand as promising targets for personalized therapeutic cancer vaccines. The identification process for neoantigens has evolved with the use of next-generation sequencing technologies and bioinformatic tools in tumor genomics. However, in silico strategies for selecting immunogenic...

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Literature Corpus work: c5cefc96-2355-5e23-bebf-9e73e6bd810d
DOI: 10.1101/2023.09.07.556652

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