Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes.

Abstract excerpt

BACKGROUND: Genetic associations link hematopoietic traits and disease end-points, but most causal variants and genes underlying these relationships are unknown. Here, we used genetic colocalization to nominate loci and genes related to shared genetic signal for hematopoietic, cardiovascular, autoimmune, neuropsychiatric, and cancer phenotypes. METHODS: Our aim was to identify colocalization sites for human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression Profiling
• Share to Gene Expression Regulation