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Article

Translational profiling of neuronal subtypes in pre-symptomatic fatal familial insomnia mice reveals TOR signaling in somatostatin-expressing neurons

2022-03-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Selective neuronal vulnerability is a common, yet poorly understood characteristic of neurodegenerative diseases. It is particularly fascinating in familial prion diseases, such as fatal familial insomnia (FFI) and Creutzfeldt-Jakob disease (CJD), where different mutants of the prion protein manifest as clinically and neuropathologically distinct diseases. <bold>M...

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Literature Corpus work
b1dbbc37-7bce-534c-a153-24c740488ce1
DOI
10.21203/rs.3.rs-1458940/v1
Open publication

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Translational profiling of neuronal subtypes in pre-symptomatic fatal familial insomnia mice reveals TOR signaling in somatostatin-expressing neuronsDOI 10.21203/rs.3.rs-1458940/v1
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