Article
Translational profiling of neuronal subtypes in pre-symptomatic fatal familial insomnia mice reveals TOR signaling in somatostatin-expressing neurons
2022-03-25
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>Selective neuronal vulnerability is a common, yet poorly understood characteristic of neurodegenerative diseases. It is particularly fascinating in familial prion diseases, such as fatal familial insomnia (FFI) and Creutzfeldt-Jakob disease (CJD), where different mutants of the prion protein manifest as clinically and neuropathologically distinct diseases. <bold>M...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- b1dbbc37-7bce-534c-a153-24c740488ce1
- DOI
- 10.21203/rs.3.rs-1458940/v1
