Article

A flow cytometry-based assay to quantify the binding of transmembrane ligands to their cognate receptors using fluorescent virus-like particles

2026-05-15

Abstract excerpt

The binding of transmembrane (TM) ligands to their cognate TM receptors on neighboring cells governs intercellular adhesion and direct cell–cell communication. However, these interactions are difficult to study in vitro because they depend on membrane presentation, ligand orientation, receptor clustering, and avidity, features often not captured by soluble recombinant ligands or cell-free assays. Here, we describe...

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Literature Corpus work: b1ccf3a2-eabd-57fc-bc4a-6162477a1621
DOI: 10.64898/2026.05.14.725198

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