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Article

Single-Particle Discrimination of Retroviruses from Extracellular Vesicles by Nanoscale Flow Cytometry.

Scientific reports - 19 Dec 2017

Tang Vera A, Renner Tyler M, Fritzsche Anna K, Burger Dylan, Langlois Marc-André

Abstract excerpt

Retroviruses and small EVs overlap in size, buoyant densities, refractive indices and share many cell-derived surface markers making them virtually indistinguishable by standard biochemical methods. This poses a significant challenge when purifying retroviruses for downstream analyses or for phenotypic characterization studies of markers on individual virions given that EVs are a major contaminant of retroviral...

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PMID: 29259315
DOI: 10.1038/s41598-017-18227-8
PMCID: PMC5736735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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