Article

Single-molecule localization microscopy reveals the molecular organization of endogenous membrane receptors

2025-08-19

Abstract excerpt

Super-resolution microscopy in combination with genetic labeling methods allows imaging of single proteins in cells. However, visualizing endogenous proteins on primary cells remains challenging due to the use of sterically demanding antibodies for labeling. Here, we demonstrate how immunolabeling conditions and antibody crosslinking influence the quantification and identification of membrane receptor stoichiometr...

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Literature Corpus work: 0042f7fe-104b-5dcd-a4b2-b423f902819c
DOI: 10.1101/2025.08.18.670816

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