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Translesion Synthesis by MmLV-, AMV-, and HIV-Reverse Transcriptases Using RNA Templates Containing Inosine, Guanosine, and Their 8-oxo-7,8-Dihydropurine Derivatives

2020-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Inosine is ubiquitous and essential in many biological processes, including RNA-editing. In addition, oxidative stress on RNA has been a topic of increasing interest due, in part, to its potential role in the development/progression of disease. In this work we probed the ability of three reverse transcriptases to catalyze the synthesis of cDNA in the presence of RNA templates containing inosine...

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Literature Corpus work
b1adf0b4-5d2f-53b3-a607-546d7674a084
DOI
10.1101/2020.06.10.144048
Open publication

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Translesion Synthesis by MmLV-, AMV-, and HIV-Reverse Transcriptases Using RNA Templates Containing Inosine, Guanosine, and Their 8-oxo-7,8-Dihydropurine DerivativesDOI 10.1101/2020.06.10.144048
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