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Article

Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.

Journal of molecular biology - 4 Apr 2008

Yasui Manabu, Suenaga Emi, Koyama Naoki, Masutani Chikahide, Hanaoka Fumio, Gruz Petr, Shibutani Shinya, Nohmi Takehiko, Hayashi Makoto, Honma Masamitsu

Abstract excerpt

Chronic inflammation involving constant generation of nitric oxide (*NO) by macrophages has been recognized as a factor related to carcinogenesis. At the site of inflammation, nitrosatively deaminated DNA adducts such as 2'-deoxyinosine (dI) and 2'-deoxyxanthosine are primarily formed by *NO and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18304575
DOI: 10.1016/j.jmb.2008.01.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18304575-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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