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Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

2020-03-23

Abstract excerpt

After acute kidney injury (AKI), patients either recover or alternatively develop fibrosis and chronic kidney disease. Interactions between injured epithelia, stroma and inflammatory cells determine whether kidneys repair or undergo fibrosis, but the molecular events that drive these processes are poorly understood. Here, we use single nucleus RNA sequencing of a mouse model of AKI to characterize cell states duri...

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Literature Corpus work
ffff1253-241d-5924-ab00-a887273760b2
DOI
10.1101/2020.03.22.002261
Open publication

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Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injuryDOI 10.1101/2020.03.22.002261
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