Article

LC3-associated phagocytosis is impaired in monocyte-derived macrophages from systemic sclerosis patients

2024-03-26

Abstract excerpt

Autophagy is a fundamental catabolic process performed by a network of autophagy related (ATG) proteins. Some ATG proteins coordinate parallel roles in so-called “noncanonical” autophagy such as LC3-associated phagocytosis (LAP). Both autophagy and LAP share key functions in immunity and inflammation and have been linked to autoimmune diseases. Systemic sclerosis (SSc) is an autoimmune disease of unknown etiology...

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Literature Corpus work: b1569d5a-eef8-53cb-9cd2-7618c84268d1
DOI: 10.1101/2024.03.21.586112

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