Article
The role of autophagy in the pathogenesis of systemic lupus erythematosus.
International immunopharmacology - 1 Nov 2016
Liu Xiao, Qin Haihong, Xu Jinhua
Abstract excerpt
Autophagy is a highly conserved catabolic process, whereby unwanted cytoplasmic contents are enclosed by the double-membrane autophagosomes and delivered to the lysosomes for degradation. It is responsible for the recycling of nutrients and cellular components, thus playing a pivotal role in maintaining cellular homeostasis as well as cell survival during stress conditions. Perturbations in autophagy are...
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