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LC3 ‐associated phagocytosis and human diseases: Insights from mechanisms to therapeutic potential

24 Oct 2024

Abstract excerpt

LC3-associated phagocytosis (LAP) is a distinct type of autophagy that involves the sequestration of extracellular material by phagocytes. Beyond the removal of dead cells and cellular debris from eukaryotic cells, LAP is also involved in the removal of a variety of pathogens, including bacteria, fungi, and viruses. These events are integral to multiple physiological and pathological processes, such as host...

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PMID: 39446073
DOI: 10.1096/fj.202402126r

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