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Article

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

26 Jul 2012

Abstract excerpt

Autophagy, the cytoprotection mechanism that takes place under metabolic impairment, has been implicated in the pathogenesis of autoimmunity. Here, we investigated the spontaneous and induced autophagic behavior of T lymphocytes from patients with systemic lupus erythematosus (SLE) compared with that of T lymphocytes from healthy donors by measuring the autophagy marker microtubule‐associated protein 1 light...

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PMID: 22835828
DOI: 10.1096/fj.12-206060

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