Article
Emerging view of autophagy in systemic lupus erythematosus.
International reviews of immunology - 1 May 2015
Zhou Xu-Jie, Cheng Fa-Juan, Zhang Hong
Abstract excerpt
Aberrations of both innate immunity and adaptive immunity in genetically predisposed individuals evoked by environmental factors are suggested to be implicated in pathophysiological processes of systemic lupus erythematosus (SLE). Autophagy, a degradation pathway in which cytoplasmic content is engulfed and degraded by the lysosome, has been recently demonstrated to be involved in multiple cytoplasmic homeostatic...
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