Article

Conservation motifs - a novel evolutionary-based classification of proteins

2020-01-14

Abstract excerpt

Cross-species protein conservation patterns, as directed by natural selection, are indicative of the interplay between protein function, protein-protein interaction and evolution. Since the beginning of the genomic era, proteins were characterized as either conserved or not conserved. This simple classification became archaic and cursory once data on protein orthologs became available for thousands of species. To...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b12ee566-0dd4-5871-994b-010a05d6b87d
DOI: 10.1101/2020.01.12.903138

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Conservation motifs - a novel evolutionary-based classification of proteinsDOI 10.1101/2020.01.12.903138Read

Prediction and discovery of protein-protein direct interactions and stable complexes based on gene co-expression and co-evolutionSemantic proximity Read

A universal trend of amino acid gain and loss in protein evolution.Semantic proximity Read

Conservation and coevolution determine evolvability of different classes of disordered residues in human intrinsically disordered proteins.Semantic proximity Read

Evolution of the protein repertoire.Semantic proximity Read

Reconstructing phylogenetic tree using a protein-protein interaction technique.Semantic proximity Read

Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciationSemantic proximity Read

New Protein Function Characterization for Human Paralog Discovery, Scraping the Bottom of the Genomics BarrelSemantic proximity Read

Genomic and structural aspects of protein evolution.Semantic proximity Read

A Functional Map of the Human Intrinsically Disordered ProteomeSemantic proximity Read

Gene families: the taxonomy of protein paralogs and chimeras.Semantic proximity Read

PANTHER: a library of protein families and subfamilies indexed by function.Semantic proximity Read

Human protein-RNA interaction network is highly stable across mammals.Semantic proximity Read