Article
Genomic and structural aspects of protein evolution.
The Biochemical journal - 1 Apr 2009
Chothia Cyrus, Gough Julian
Abstract excerpt
It has been known for more than 35 years that, during evolution, new proteins are formed by gene duplications, sequence and structural divergence and, in many cases, gene combinations. The genome projects have produced complete, or almost complete, descriptions of the protein repertoires of over 600 distinct organisms. Analyses of these data have dramatically increased our understanding of the formation of new...
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