Article

Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart

2026-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Epigenetic modulators such as histone deacetylases (HDACs) and histone acetyltransferases (HATs) are known master regulators of gene expression that substantially impact cardiac electrophysiology. Novel pharmacological agents, HDAC inhibitors, are rapidly emerging as treatments for cancer and immune diseases, and their effects on cardiac ion channels (ICs) are of great interest. We used small in...

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Literature Corpus work: b1223549-5e7d-5fc0-8ef5-300314e9c08a
DOI: 10.64898/2026.01.16.700033

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Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heartDOI 10.64898/2026.01.16.700033Read

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