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Constructing a full-length single-nucleus transcriptomic atlas of the obese mouse by UURNA-seq

2026-07-20

Abstract excerpt

Single-nucleus RNA-seq (snRNA-seq) offers advantages in sample preparation for atlas construction and data mining of gene regulation. However, current snRNA-seq protocols struggle to balance sensitivity and throughput. Here we present ultra-throughput and ultra-sensitivity single-nucleus total RNA sequencing (UURNA-seq), a platform that enables large-scale atlas construction in a single day. UURNA-seq outperforms...

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Literature Corpus work
b1200e31-e07b-52a4-b7c6-18d2052474fc
DOI
10.64898/2026.07.14.738381
Open publication

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