Article

Single-nucleus RNA sequencing reveals cellular and molecular dynamics of white and brown adipose tissue in a mouse model of type-2 diabetes

2024-02-07

Abstract excerpt

<h4>Summary</h4> Excessive adipose tissue expansion is often linked with type-2 diabetes. Despite recent efforts mapping adipose tissue changes in obesity using single-cell omics, an understanding of cellular and gene expression changes in a model of type 2 diabetes, and the transcriptional circuitry controlling it, is still lacking. Here, we use single-nucleus RNA sequencing to analyze the remodeling of gonadal...

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Literature Corpus work: 7fe8176d-fb6d-5651-9586-dbaedbb2a1f5
DOI: 10.1101/2024.02.06.578860

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