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Mapping the transcriptional landscape of human white and brown adipogenesis using single-nuclei RNA-seq

5 Jun 2023

Abstract excerpt

Adipogenesis is key to maintaining organism-wide energy balance and healthy metabolic phenotype, making it critical to thoroughly comprehend its molecular regulation in humans. By single-nuclei RNA-sequencing (snRNA-seq) of over 20,000 differentiating white and brown preadipocytes, we constructed a high-resolution temporal transcriptional landscape of human white and brown adipogenesis. White and brown...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 37286033
DOI: 10.1016/j.molmet.2023.101746

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