Article

Integration of HLA-DR linkage disequilibrium to MHC class II predictions

2023-05-24

Abstract excerpt

Insights into peptide binding to HLA class II molecules is essential when studying the biological mechanisms behind cellular immunity, autoimmune diseases, and the development of immunotherapies and peptide vaccines. Currently, most of the publicly available data used to train state-of-the-art binding prediction methods for HLA-DR only includes DRB1 information. The role of the paralogue alleles, HLA-DRB3/4/5, and...

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Literature Corpus work: b11e517a-f407-574f-98fb-de3b4235a41c
DOI: 10.1101/2023.05.24.542040

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