Article

Molecular determinants of fibrillation in a viral amyloidogenic domain from combined biochemical and biophysical studies

2022-11-02

Abstract excerpt

The Nipah and Hendra viruses (NiV and HeV ) are biosafety level 4 human pathogens classified within the Henipavirus genus of the Paramyxoviridae family. In both NiV and HeV, the gene encoding the Phosphoprotein (P protein), an essential polymerase cofactor, also encodes the V and W proteins. These three proteins, which share an intrinsically disordered N-terminal domain (NTD) and have unique C-terminal domains...

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Literature Corpus work: b101b5ef-7886-5b7e-a386-ce5964ec4e2d
DOI: 10.1101/2022.11.02.514851

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