Article

Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through intrinsic apoptosis in the neonatal lung

2025-06-15

Abstract excerpt

<h4>ABSTRACT</h4> Lung myofibroblasts are necessary for early postnatal alveolar growth and develop again during pathological fibrosis. Determining the unique contributions of multiple myofibroblast lineages to development and disease is hampered by a lack of genetic tools to distinguish between them. In this study, we generated a Stc1 CreERT2 mouse line that faithfully labels the developmentally transient seco...

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Literature Corpus work: b0f8ca1c-48e6-59d8-a441-2f0d5bcb67f1
DOI: 10.1101/2025.06.12.659126

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