Article

Embedding muscle fibers in hydrogel improves viability and preserves contractile function during prolonged <i>ex vivo</i> culture

2025-01-15

Abstract excerpt

Ex vivo culture of isolated muscle fibers can serve as an important model for in vitro research on mature skeletal muscle fibers. Nevertheless, this model has limitations for long-term studies due to structural loss and dedifferentiation following prolonged culture periods. This study aimed to investigate how ex vivo culture affects muscle fiber contraction and to improve the culture system to preserve muscle fi...

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Literature Corpus work: b0bcdb17-693a-5875-88e7-939df4495040
DOI: 10.1101/2025.01.13.632729

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