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Dissociated flexor digitorum brevis myofiber culture system—A more mature muscle culture system

24 Jul 2007

Abstract excerpt

Considerable knowledge regarding skeletal muscle physiology and disease has been gleaned from cultured myoblastic cell lines or isolated primary myoblasts. Such muscle cultures can be induced to differentiate into multinucleated myotubes that become striated. However they in general do not fully mature and therefore do not model mature muscle. Contrastingly, fresh and cultured dissociated adult mouse flexor...

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PMID: 17654606
DOI: 10.1002/cm.20223

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