Article

3D Human Induced Pluripotent Stem Cell-derived Bioengineered Skeletal Muscles for Tissue, Disease and Therapy Modelling

2022-09-06

Abstract excerpt

<title>Abstract</title> <p>Skeletal muscle is a complex tissue composed of multinucleated myofibres responsible for force generation, supported by multiple cell types. Many severe and lethal disorders affect skeletal muscle; therefore, engineering models to reproduce such cellular complexity and function is instrumental for investigating muscle pathophysiology and developing therapies. Here, we detail the modular...

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Literature Corpus work: fe564f72-9939-5c49-8853-853d75cd2e4f
DOI: 10.21203/rs.3.pex-2034/v1

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