Article

Human iPSC-derived motor neuron innervation enhances the differentiation of muscle bundles engineered with benchtop fabrication techniques

2024-12-05

Abstract excerpt

Engineered skeletal muscle tissues are critical tools for disease modeling, drug screening, and regenerative medicine, but are limited by insufficient maturation. Because innervation is a critical regulator of skeletal muscle development and regeneration in vivo, motor neurons are hypothesized to improve the maturity of engineered skeletal muscle tissues. Although motor neurons have been added to pre-engineered mu...

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Literature Corpus work: ce2f7ee6-7cff-5130-8990-41975261b795
DOI: 10.1101/2024.12.02.626391

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