Article

3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients

2019-01-17

Abstract excerpt

Mutation profiles of Glioblastoma (GBM) tumors are very heterogeneous which is the main challenge in the interpretation of the effects of mutations in disease. Additionally, the impact of the mutations is not uniform across the proteins and protein-protein interactions. The pathway level representation of the mutations is very limited. In this work, we approach these challenges through a systems level perspective...

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Literature Corpus work: b04c45a1-dd8b-5f04-8d67-5c8d2614c826
DOI: 10.1101/523563

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