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Article

Depression in Premanifest Huntington’s Disease: Aberrant Effective Connectivity of Striatum and Default Mode Network

2024-03-18

Abstract excerpt

2. <h4>Background</h4> Depression frequently precedes motor symptoms in Huntington’s disease gene expansion carriers (HDGECs), yet the neural mechanisms remain poorly characterized. <h4>Objectives</h4> We investigated effective connectivity between the default mode network and striatal regions in HDGECs. <h4>Methods</h4> We analyzed 3T resting-state functional magnetic resonance imaging data from 98 HDGECs (48....

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Literature Corpus work
b02306ae-1cbd-5d46-9081-f6184fb1ca62
DOI
10.1101/2024.03.17.24304066
Open publication

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Depression in Premanifest Huntington’s Disease: Aberrant Effective Connectivity of Striatum and Default Mode NetworkDOI 10.1101/2024.03.17.24304066
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