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Safeguarding <i>Drosophila</i> female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

2022-09-04

Abstract excerpt

H3K9me3-based gene silencing is a conserved strategy for securing cell fate, but the mechanisms controlling lineage-specific installation of this epigenetic mark remain unclear. In Drosophila , H3K9 methylation plays an essential role in securing female germ cell fate by silencing lineage inappropriate phf7 transcription. Thus, phf7 regulation in the female germline provides a powerful system to dissect the mol...

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Literature Corpus work
b01f09f5-61ae-5f83-ad0b-0fc02d0ef8b5
DOI
10.1101/2022.09.04.506543
Open publication

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Safeguarding <i>Drosophila</i> female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger proteinDOI 10.1101/2022.09.04.506543
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