Article

Chondrogenic Enhancer Landscape of Limb and Axial Skeleton Development

2023-05-11

Abstract excerpt

The precisely orchestrated differentiation of chondrocytes during skeleton development is a critical determinant of human height and body shape and disruptions of this process can cause severe skeletal abnormalities. The ultimate size and shape of each of over 200 bones depends on the intricate spatiotemporal regulation of chondrogenic and chondrocyte differentiation genes, but the genomic architecture coordinatin...

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Literature Corpus work: b0115eb4-4c77-5858-a876-a6e21b686427
DOI: 10.1101/2023.05.10.539849

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