Article

Imaging Architecture of Granulomas Induced by <i>Mycobacterium tuberculosis</i> Infections with Single-Molecule FISH

2023-02-03

Abstract excerpt

Granulomas are an important hallmark of Mycobacterium tuberculosis ( Mtb ) infection. They are organized and dynamic structures created by an assembly of immune cells around the sites of infection in the lungs to locally restrict the bacterial growth and the host’s inflammatory responses. The cellular architecture of granulomas is traditionally studied by immunofluorescence labeling of phenotypic surface markers...

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Literature Corpus work: aff31586-30a8-501e-af0b-5411dc205bc6
DOI: 10.1101/2023.02.02.526702

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