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Direct visualization of bacterial transcripts in the infected lung illuminates spatiotemporal environmental adaptation of Mycobacterium tuberculosis

2025-08-25

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<h4>SUMMARY</h4> Spatiotemporal environmental variation results in marked heterogeneity in bacterial infection progression and disease outcome, with vital consequences for treatment success. For the globally important pathogen Mycobacterium tuberculosis (Mtb), while the pronounced intra-host spatial heterogeneity in lesion immune cell composition and phenotype has been well-described, the highly complex Mtb cell...

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Literature Corpus work: d5bc3659-cf09-55d1-a15b-cc835bed3672
DOI: 10.1101/2025.08.25.672169

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Direct visualization of bacterial transcripts in the infected lung illuminates spatiotemporal environmental adaptation of <i>Mycobacterium tuberculosis</i>

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