Article

A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages

2017-11-02

Abstract excerpt

The primary target of Influenza A virus (IAV) is epithelial cells in the respiratory tract. In contrast to epithelial cells, productive infection of most IAV strains is either blocked or highly inefficient in macrophages. The exact nature of the defect in IAV replication in human macrophages remains unknown. In this study, we showed that primary human monocyte-derived macrophages (MDM) are inefficient in IAV relea...

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Literature Corpus work: afe3a4de-7992-5a78-9b3d-cd2d2deb5d78
DOI: 10.1101/213447

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