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Article

The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages.

BMC biology - 23 Jun 2016

Nkwe David O, Pelchen-Matthews Annegret, Burden Jemima J, Collinson Lucy M, Marsh Mark

Abstract excerpt

BACKGROUND: In HIV-infected macrophages, newly formed progeny virus particles accumulate in intracellular plasma membrane-connected compartments (IPMCs). Although the virus is usually seen in these compartments, it is unclear whether HIV assembly is specifically targeted to IPMCs or whether some viruses may also form at the cell surface but are not detected, as particles budding from the latter site will be...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27338237
DOI: 10.1186/s12915-016-0272-3
PMCID: PMC4919869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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