Article

A human-specific microRNA controls the timing of excitatory synaptogenesis

2023-10-05

Abstract excerpt

Neural circuit development in the human cortex is considerably prolonged in comparison to non-human primates, a trait that contributes to the remarkable cognitive capacity of modern humans. Here, we explore the regulatory role of non-coding RNAs, which dramatically expanded during brain evolution, in synapse development of human-induced pluripotent stem-cell derived neurons. We found that inhibition of a human-spe...

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Literature Corpus work: afccd49d-3835-5201-8645-a58b67c8ef4d
DOI: 10.1101/2023.10.04.560889

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