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Article

Deconstructing the neuropathic pain phenotype to reveal neural mechanisms.

Neuron - 23 Feb 2012

von Hehn Christian A, Baron Ralf, Woolf Clifford J

Abstract excerpt

After nerve injury maladaptive changes can occur in injured sensory neurons and along the entire nociceptive pathway within the CNS, which may lead to spontaneous pain or pain hypersensitivity. The resulting neuropathic pain syndromes present as a complex combination of negative and positive symptoms, which vary enormously from individual to individual. This variation depends on a diversity of underlying...

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Identifiers

PMID: 22365541
DOI: 10.1016/j.neuron.2012.02.008
PMCID: PMC3319438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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