Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hoxb8‐Cre mice: A tool for brain‐sparing conditional gene deletion

23 Jul 2010

Abstract excerpt

The spinal cord is the first site of temporal and spatial integration of nociceptive signals in the pain pathway. Neuroplastic changes occurring at this site contribute critically to various chronic pain syndromes. Gene targeting in mice has generated important insights into these processes. However, the analysis of constitutive (global) gene-deficient mice is often hampered by confounding effects arising from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axon Guidance and Neuronal Signaling
Share to Neuropeptides and Animal Physiology
Share to Pain Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20658520
DOI: 10.1002/dvg.20656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hoxb8‐Cre mice: A tool for brain‐sparing conditional gene deletionPMID 20658520Read ↗

Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice.Semantic proximity Read ↗

Pain genes.Semantic proximity Read ↗

Mice lacking spinal α2GABAA receptors: Altered GABAergic neurotransmission, diminished GABAergic antihyperalgesia, and potential compensatory mechanisms preventing a hyperalgesic phenotype.Semantic proximity Read ↗

A role for LGI1 in regulating pain sensitivitySemantic proximity Read ↗

Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and HumansSemantic proximity Read ↗

Chronic pain: genes, plasticity, and phenotypes.Semantic proximity Read ↗

Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases.Semantic proximity Read ↗

MeCP2 Plays an Analgesic Role in Pain Transmission through Regulating CREB / miR-132 PathwaySemantic proximity Read ↗

Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord.Semantic proximity Read ↗

A validated set of neural gene reporter mice and chemical tracer tools for mapping knee innervating neuronsSemantic proximity Read ↗

Pain genes?: natural variation and transgenic mutants.Semantic proximity Read ↗

Nociceptor-restricted cannabinoid receptor 1 contributes to chronic but not acute analgesiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.