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<i>Pseudomonas aeruginosa lasR</i> is a keystone gene in polymicrobial cultures

2025-10-06

Abstract excerpt

The airways of people with cystic fibrosis (CF) are often co-infected by Pseudmonas aeruginosa and a variety of other co-habiting microbes; the infections are polymicrobial. P. aeruginosa isolates from the CF airways are also known to commonly acquire mutations in the quorum sensing regulator, lasR . The appearance of these lasR mutants is associated with a worsening clinical prognosis. In this work, we show t...

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Literature Corpus work
afc423e6-82e7-5a79-a981-0116861bda41
DOI
10.1101/2025.10.06.680631
Open publication

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