Article

Non-hierarchical, RhlR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of <i>Pseudomonas aeruginosa</i>

2019-09-02

Abstract excerpt

<h4>ABSTRACT</h4> The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in cystic fibrosis (CF) patients. P. aeruginosa employs several hierarchically arranged and interconnected quorum sensing (QS) regulatory circuits to produce a battery of virulence factors such as elastase, phenazines, and rhamnolipids. The QS transcription factor LasR sits atop this hierarchy, and activat...

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Literature Corpus work: 01f331a3-af63-5d80-9a3f-5a3b302112cb
DOI: 10.1101/755314

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