Article

Creatine transporter (Slc6a8) knockout mice show an inattentive-like phenotype in the 5-choice serial reaction time test

2022-06-03

Abstract excerpt

Disorders of creatine (Cr) synthesis and transport cause moderate to severe intellectual disability, epilepsy, and a lack of speech development. Mutations of the X-linked Cr transporter (CrT; SLC6A8 ) gene are the most frequent cause of Cr deficiency and one of the leading causes of X-linked intellectual disability. There are no treatments for CrT deficiency (CTD) and there are many unanswered questions related t...

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Literature Corpus work: afbedcef-a58d-59b1-8043-04a04be3ceb9
DOI: 10.1101/2022.06.02.494536

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