Article

Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State

2024-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Inter-cellular transmission of mRNA is being explored in mammalian species using immortal cell lines (1–3). Here, we uncover an inter-cellular mRNA transfer phenomenon that allows for the adaptation and reprogramming of human primed pluripotent stem cells (hPSCs). This process is induced by the direct cell contact-mediated coculture with mouse embryonic stem cells (mESCs) under the condition imp...

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Literature Corpus work: afac1c6b-c862-58fb-96b1-e0eae1eb6438
DOI: 10.1101/2024.06.27.600209

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